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EPIRUBICIN 10MG INJECTION (EPITERO 50MG)
DESCRIPTION
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PACKAGE
Medicine Details
Brand Name: Epitero
Generic Name: Epirubicin
Manufacturer: Hetero
Dosage Form: Injection
Strength: 10mg and 50mg
Composition: Epirubicin
Packaging: 1vial
Indication: Blood cancer, Breast cancer, Stomach cancer, and Lung cancer.
Storage: Store at room temperature
Overview
Epitero (Epirubicin) injection is used in the treatment of certain types of cancers (breast cancer, blood cancer, stomach cancer, and lung cancer). This medicine belongs to a group of cancer-fighting medications known as antineoplastics, and specifically to the class of drugs known as anthracyclines. It works by suppressing the activity of (topoisomerase II) involved in the DNA multiplication of breast cancer cells. It is important to take Epitero injection as prescribed by your doctor. The recommended dose of Epitero injection is decided by a doctor according to your previous medical condition and response to the treatment. This medicine is given as an infusion into your vein. Do not self-administer this medicine. Close monitoring of blood cell count and liver function is required while having treatment with this medicine.
Pharmacodynamics
Epirubicin is an anthracycline cytotoxic agent. Although it is known that anthracyclines can interfere with several biochemical and biological functions within eukaryotic cells, the precise mechanisms of Epirubicin’s cytotoxic and/or antiproliferative properties have not been completely elucidated. It forms a complex with DNA by intercalation of its planar rings between nucleotide base pairs, with consequent inhibition of nucleic acid (DNA and RNA) and protein synthesis.
Usage
This medication is used to treat breast cancer. It helps to stop the growth of cancer cells and also prevents the multiplication of cancer cells. This medicine comes in the form of infusion and it is given by your doctor or nurse. Avoid contact with people who have infections. It is advisable not to change or stop the dose without taking suggestions from your doctor. Do not take this medicine in the wrong way as it may lead to serious side effects.
Interactions
Epitero injection can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.
Medicine Interactions
- Adalimumab
- Dofetilide
- Clozapine
- Etanercept
- Ketoconazole
- Ribociclib
Disease Interactions
- Heart disease
- Renal impairment
- Neutropenia
- Liver disease
Alcohol Interaction
- Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.
Contraindications
- Do not take this medicine if you are allergic to Epirubicin.
- Epitero (Epirubicin)medicine is not recommended in patients known to be hypersensitive.
Substitutes
- Epicure
- Biorubin
- Innorubicin
Side Effects
This medicine may cause some mild or serious side effects. Discuss the risks and benefits of Epitero injection with the doctor before starting the treatment.
Common Side Effects
- Diarrhea
- Chest pain
- Loss of appetite
- Sore throat
- Ulcers
- Irregular menstrual periods
- Skin rash
- Abdominal pain
- Hair loss
- Weight loss
- Unusual drowsiness
- Pain at the injection site
- Swelling of the lining of the mouth
- Anxiety
- Pale skin
- Bleeding
- Unusual tiredness
- Coughing up blood
- Back pain
- Dehydration
- Vomiting
- Dizziness
- Chest pain
- Unusual weakness
Serious Side Effects
- Low white blood cell count
- Red spots on the skin
- Irregular heartbeat
- Joint pain
- Fever
- Blood in urine and stools
- Chills
Note – immediately contact your medical practitioner if any side effects occur.
Warnings
Before starting treatment with Epitero medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.
- Contraception
- Use suitable methods of contraception to prevent pregnancy while taking this medicine.
- Children and adolescents
- Epitero injection is not advisable for use in children.
Warnings For Female
- Pregnancy
- Do not use Epitero medicine if you are planning to become pregnant. Avoid this medication at the time of pregnancy.
- Breastfeeding
- This medicine is not recommended in breastfeeding unless it is essential. Please consult with your doctor before starting treatment with this medication.
Precautions
- This medicine may decrease the white blood cell and platelets.
- Epitero injection should be used with caution in patients suffering from kidney injury.
- Close monitoring of blood cell count and liver function is required while receiving this medication.
- It may increase the risk of infections. Avoid contact with people who have infections.
- Inform your doctor if you experience any side effects like – diarrhea, chest pain, irregular heartbeat, joint pain, fever, etc.
- Do not skip the scheduled dose of this medicine.
Cautions
- Do not drive or operate heavy machinery.
- Do not self-administer.
- Not safe for pregnant women.
- Do not breastfeed while receiving this medication.
